Christine Schwienbacher studied Biology at the University of Ferrara and obtained her Degree in Biological Sciences in 1991, her Ph.D. in Cellular and Molecular Biology in 1995, and her Specialization in Clinical Pathology in 2000 from the University of Ferrara. Christine worked as Postdoc in Ferrara and Braunschweig, as Laboratory assistant and finally as Researcher at the University of Ferrara. She joined the Institute of Genetic Medicine in September 2007 for a sabbatical year, and her current main research interest is the identification of genes, especially miRNA genes, involved in genetically caused diseases of the local population.
Publications
1. RFLPS AND GENE LESIONS IN DISORDERS OF HAEMOSTASIS
F Bernardi, G Marchetti, P Patracchini, D Gemmati, C Schwienbacher S Boninsegna and F Conconi
In: DNA analysis of genetic diseases: state-of-the-art in Italy
Edited by M Pirastu, C Camaschella, G Morpurgo, M Polsinelli 2:5-8 (1988)
2. CHROMOSOMAL LOCALIZATION AND CHARACTERIZATION OF RFLPs IN THE VON WILLEBRAND FACTOR PSEUDOGENE
G Marchetti, P Patracchini, V Aiello, S Boninsegna, C Schwienbacher, E Calzolari and F Bernardi
In: DNA analysis of genetic diseases: state-of-the-art in Italy II
Edited by C Camaschella, M Furbetta, P Merlin, M Pirastu 3:150-152 (1989)
3. A RECURRENT MISSENSE MUTATION (Arg -> Gln) AND A PARTIAL DELETION IN FACTOR VIII GENE CAUSING SEVERE HAEMOPHILIA A
F Bernardi, S Volinia, P Patracchini, D Gemmati, S Boninsegna, C Schwienbacher and G Marchetti
British Journal of Haematology 71:271-276 (1989)
4. CHARACTERIZATION BY PCR AND SEQUENCING OF A "DE NOVO" AND HETEROZYGOUS GENE DELETION CAUSING A DOMINANT VARIANT OF VON WILLEBRAND DISEASE
G Marchetti, P Patracchini, D Gemmati, S Moratelli, C Schwienbacher, M Prendin, G Ballerini and F Bernardi
In: DNA analysis of genetic diseases: state-of-the-art in Italy III
Edited by C Camaschella, M Furbetta, P Merlin, M Pirastu 6:116-120 (1991)
5. CHARACTERIZATION OF THE PSEUDOGENIC AND GENIC HOMOLOGOUS REGIONS OF VON WILLEBRAND FACTOR
G Marchetti, P Patracchini, S Volinia, V Aiello, M Schiavoni, N Ciavarella, E Calzolari, C Schwienbacher and F Bernardi
British Journal of Haematology 78:71-79 (1991)
6. PREFERENTIAL BINDING OF ALPHA-ACTININ TO ACTIN BUNDLES
E Grazi, P Cuneo, E Magri and C Schwienbacher
FEBS Letters 314: 348-350 (1992)
7. IN FRAME DELETION OF VON WILLEBRAND FACTOR A DOMAINS IN A DOMINANT TYPE OF VON WILLEBRAND DISEASE
F Bernardi, P Patracchini, D Gemmati, M Pinotti, C Schwienbacher, G Ballerini and G Marchetti
Human Molecular Genetics 2:545-548 (1993)
8. DIFFUSION HINDRANCE AND GEOMETRY OF FILAMENT CROSSINGS ACCOUNT FOR THE COMPLEX INTERACTIONS OF F-ACTIN WITH ALPHA-ACTININ FROM CHICKEN GIZZARD
E Grazi, P Cuneo, E Magri, C Schwienbacher and G Trombetta
Biochemistry 32:8896-8901 (1993)
9. OSMOTIC STRESS IS THE MAIN DETERMINANT OF THE DIAMETER OF THE ACTIN FILAMENT
E Grazi, C Schwienbacher, E Magri
Biochemical and Biophysical Research Communications 197: 1377-1381 (1993)
10. ALPHA-ACTININ FROM CHICKEN GIZZARD. AT LOW TEMPERATURE, THE ONSET OF ACTIN GELLING ACTIVITY CORRELATES WITH ACTIN BUNDLING
E Grazi, G Trombetta, E Magri, P Cuneo and C Schwienbacher
Biochemical Journal 298: 129-133 (1994)
11. ACTIN MAY CONTRIBUTE TO THE POWER STROKE IN THE BINARY ACTO-MYOSIN SYSTEM
E Grazi, E Magri, C Schwienbacher and G Trombetta
Biochemical and Biophysical Research Communications 200: 59-64 (1994)
12. OSMOTIC PROPERTIES OF THE CALCIUM-REGULATED ACTIN FILAMENT
C Schwienbacher, E Magri, G Trombetta and E Grazi
Biochemistry 34: 1090-1095 (1995)
13. OSMOTIC PROPERTIES OF THE MYOSIN SUBFRAGMENT 1: IMPLICATIONS ON THE MECHANISM OF MUSCLE CONTRACTION
E Grazi, E Magri, C Schwienbacher and G Trombetta
Archives of Biochemistry and Biophysics 322: 97-102 (1995)
14. INTRAMOLECULAR INTERACTIONS REGULATE SERINE/THREONINE PHOSPHORYLATION OF VINCULIN
C Schwienbacher, B M Jockusch and M Rüdiger
FEBS letters 384: 71-74 (1996)
15. THE STIFFNESS OF THE CROSSBRIDGE IS A FUNCTION OF THE INTRINSIC PROTEIN OSMOTIC PRESSURE GENERATED BY THE CROSSBRIDGE ITSELF
E Grazi, E Magri, C Schwienbacher, G Trombetta
FEBS letters 387: 101-104 (1996)
16. A MODEL RELATING PROTEIN OSMOTIC PRESSURE TO THE STIFFNESS OF THE CROSS-BRIDGE COMPONENTS AND THE CONTRACTILE FORCE OF SKELETAL MUSCLE
E Grazi, E Magri, C Schwienbacher and G Trombetta
Eur. J. Biochem. 241: 25-31 (1996)
17. REFINED SUBCHROMOSOMAL LOCATION OF 21 EXPRESSED SEQUENCE TAGS FROM UNKNOWN GENES AT REGION 11p15
C Schwienbacher, S Sabbioni, G Barbanti-Brodano, M Negrini
European Journal of Human Genetics 5: 214-217 (1997)
18. TRANSCRIPTIONAL MAP OF 170 kb REGION AT CHROMOSOME 11p15.5: IDENTIFICATION AND MUTATIONAL ANALYSIS OF BWR1A GENE REVEALS THE PRESENCE OF MUTATIONS IN TUMOR SAMPLES
C Schwienbacher, S Sabbioni, M Campi, A Veronese, G Bernardi, A Menegatti, I Hatada, T Mukai, H Ohashi, G Barbanti-Brodano, C M Croce, and M Negrini
Proc. Natl. Acad. Sci USA 95: 3873- 3878 (1998)
19. DIFFERENTIAL ACTIN ORGANIZATION BY VINCULIN ISOFORMS: IMPLICATIONS FOR CELL TYPE-SPECIFIC MICROFILAMENT ANCHORAGE
M Rüdiger, N Korneeva, C Schwienbacher, E E Weiss, and B M Jockusch
FEBS letters: 431: 49-54 (1998)
20. ABNORMAL RNA EXPRESSION OF 11p15 IMPRINTED GENES AND KIDNEY DEVELOPMENTAL GENES IN WILMS' TUMOR
C Schwienbacher, A Angioni, R Scelfo, A Veronese, G A Calin, G Massazza, I Hatada, G Barbanti-Brodano, and M Negrini
Cancer Research 60: 1521-1525 (2000)
21. GAIN OF IMPRINTING AT CHROMOSOME 11p15: A PATHOGENETIC MECHANISM IDENTIFIED IN HUMAN HEPATOCARCINOMAS
C Schwienbacher, L Gramantieri, R Scelfo, A Veronese, G A Calin, L Bolondi, C M Croce, G Barbanti-Brodano, and M Negrini
Proc. Natl. Acad. Sci USA 97: 5445-5449 (2000)
22. LOSS OF METHYLATION AT CHROMOSOME 11p15.5 IS COMMON IN HUMAN ADULT TUMORS
RA Scelfo, C Schwienbacher, A Veronese, L Gramantieri, L Bolondi, P Querzoli, I Nenci, GA Calin, A Angioni, G Barbanti-Brodano, M Negrini
Oncogene 21(16): 2564-72 (Apr 11; 2002)
23. NUP98 IS FUSED TO THE NSD3 GENE IN ACUTE MYELOID LEUKEMIA ASSOCIATED WITH t(8;11)(p11.2;p15)
R Rosatti, R La Starza, A Veronese, A Aventin, C Schwienbacher, T Vallespi, M Negrini, MF Martelli, C Mecucci
Blood 99(10):3857-60 (May 15; 2002)
24. MECHANISMS CAUSING IMPRINTING DEFECTS IN FAMILIAL BECKWITH-WIEDEMANN SYNDROME WITH WILMS' TUMOUR.
A Sparago, S Russo, F Cerrato, S Ferraiolo, P Castorina, A Selicorni, C Schwienbacher, M Negrini, G Battista Ferrero, M Cirillo Silengo, C Anichini, L Larizzza, A Riccio
Human Molecular Genetics 1;16(3):254-64 (2007 Feb)
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