Institute for Mummy Studies - Projects - MUMMY ATHEROSCLEROSIS
MUMMY ATHEROSCLEROSIS
Assessment of missing links in atherogenesis via paleogenetic, computed tomography and stable isotopic investigations
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- Project duration: -
- Project status: ongoing
- Funding: Internal funding EURAC (Project)
- Total project budget: €691,000.00
In this project we are planning to investigate the evolution of known and novel genetic and environmental causes of atherosclerosis. In particular, the presence and extent of atherosclerosis with genetic and environmental factors will be compared in different study populations. The populations are composed of artificial and natural mummies from cultures across the globe dating back to 6,000 years Before Present (BP). Additionally, the genomes of these populations will be compared to early human populations including Neanderthals and the Denisova hominid. The investigation techniques include the confirmation of phenotypic evidence for atherosclerosis in mummies by using x-ray computed tomography. Biopsy samples will be analysed through next generation sequencing and stable isotope analyses.
The results will be used to assess atherosclerotic burden in past populations and with the genomic analysis the genomes of the studied populations can be correlated to the phenotype.
Wurst C, Maixner F, Valverde G, Tessmann B, Krause-Kyora B, Krause J, Del Vesco P, Helmbold-Doyé J, Hotz G, Thompson R, Zink A (2022)
Presentation/Speech
Conference: 10th World Congress on Mummy Studies | Bolzano | 5.9.2022 - 9.9.2022
Mussauer A, Wurst C, Paladin A, Coia V, Maixner F, Helmbold-Doyé J, Del Vesco P, Rosendahl W, Zink A (2022)
Presentation/Speech
Conference: 10th World Congress on Mummy Studies | Bolzano | 5.9.2022 - 9.9.2022
Maixner F, Gresky J, Zink A (2021)
Journal article
International Journal of Paleopathology
More information: https://doi.org/10.1016/j.ijpp.2021.04.009
Panzer S, Augat P, Sprenger M, Zesch S, Rosendahl W, Sutherland ML, Thompson RC, Paladin A, Zink A (2021)
Journal article
International Journal of Paleopathology
More information: https://doi.org/10.1016/j.ijpp.2021.04.004
Wurst C, Paladin A, Wann LS, Frohlich B, Fritsch KO, Rowan CJ, Sutherland ML, Sutherland JD, Michalik D, Allam AH, Zesch S, Rosendahl W, Seyfried F, Thompson RC, Thomas GS, Zink A (2020)
Journal article
Journal of Archaeological Science: Reports
Wurst C, Maixner F, Zink A, The HORUS Study Team (2019)
Presentation/Speech
Conference: EMBO Practical Course - Bioinformatics and genome analyses | San Michele all'Adige | 16.6.2019 - 30.6.2019
Zink A, Samadelli M, Gostner P, Piombino-Mascali D (2019)
Journal article
International Journal of Paleopathology
Frohlich B, Wurst C, Paladin A, Zink A (2017)
Presentation/Speech
Conference: Horus-Eurac conjoint symposium on the fundamental etiologies of atherosclerosis | Torino | 1.4.2017 - 1.4.2017
Wurst C (2017)
Presentation/Speech
Conference: Horus-Eurac conjoint symposium on the fundamental etiologies of atherosclerosis | Torino | 1.4.2017 - 1.4.2017
Wurst C, Maixner F, Coia V, Zink A (2017)
Presentation/Speech
Wurst C, Wann S, Thompson R, Maixner F, Allam A, Finch C, Frohlich B, Sutherland L, Sutherland J, Narula N, Narula J, Fritsch K, Rowan C, Michalik D, Paladin A, Zesch S, Rosendahl W, Huppertz A, Seyfried F, Thomas G, Zink A (2016)
Presentation/Speech
Conference: 9th World Congress on Mummy Studies | Lima | 10.8.2016 - 13.8.2016
Wurst C, Wann S, Thompson R, Keller A, Maixner F, Allam A, Finch C, Frohlich B, Kaplan H, Lombardi G, Sutherland L, Sutherland J, Watson L, Cox S, Miyamoto M, Narula J, Stewart A, Thomas G, Zink A (2015)
Presentation/Speech
Conference: 83rd EAS Congress | Glasgow | 22.3.2015 - 25.3.2015
