PopGenCT Ancient Egypt

Life and death in ancient Egypt – Computed tomographic and paleogenetic examinations for the reconstruction of living conditions, diseases and the ancestry of Egyptian mummies

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  • Project duration: -
  • Project status: ongoing
  • Funding:
    Internal funding EURAC (Project)
  • Institute: Institute for Mummy Studies

In this project, we aim to investigate the population genetic history of Egypt using ancient DNA (aDNA) analyses. For this, Egyptian mummies and skeletal remains housed in the collections of the Museo Egizio of Turin and the Egyptian Museum and Papyrus Collection of the Staatliche Museen zu Berlin will be analyzed. These specimens encompass a time span of about 5000 years (4000 BC - AD 800) and have been recovered from various archaeological sites in Egypt. Thus, the data obtained by this project will, for the first time, cover all periods of ancient Egyptian history as well as a broad geographical context. To all specimens high-throughput sequencing methods, including DNA hybridization capture techniques, will be applied, to reconstruct mitochondrial genomes and, for specimens exhibiting a good DNA preservation, also whole-genome datasets. Thereby, this project will investigate the genetic history of Egypt not only on a uniparental level, based on the maternal lineage, but also on a genome-wide scale.    

Furthermore, in collaboration with the University of Lausanne, Switzerland, some of the mummies will be examined by means of computed tomography (CT) in the framework of a methodological test. In particular, the test aims to assess the applicability of two sex determination methods, the Ischio-Pubic Index (IPI) and the Diagnose Sexuelle Probabiliste (DSP), to CT scans, which will provide further insights into the possibilities and limitations of CT-based examinations of mummified human remains.

Publications
Atherosclerotic cardiovascular disease in mummies: a polygenic risk score based on a genetic enrichment approach
Wurst C, Maixner F, Paladin A, Mussauer A, Valverde G, Thompson R, Zink A (2023)
Presentation/Speech

Conference: New Horizons in Biomolecular Archaeology (ISBA10) | Tartu | 13.9.2023 - 16.9.2023

Genetic study of ancient Egyptian human remains dating from the Predynastic Period to the early Islamic Period (ca. 4000 cal. BCE - 800 cal. CE)
Mussauer A, Wurst C, Paladin A, Coia V, Maixner F, Zink A (2023)
Presentation/Speech

Conference: New Horizons in Biomolecular Archaeology (ISBA10) | Tartu | 13.9.2023 - 16.9.2023

Four thousand years of maternal ancestry in ancient Egypt illuminated by mitochondrial genome sequencing
Mussauer A, Wurst C, Paladin A, Coia V, Maixner F, Helmbold-Doyé J, Del Vesco P, Rosendahl W, Zink A (2022)
Presentation/Speech

Conference: 10th World Congress on Mummy Studies | Bolzano | 5.9.2022 - 9.9.2022

Facial depiction of a Roman Period mummy with portrait from the Fayoum Oasis, Egypt

Liu J, Wilkinson C, Roch A, Zesch S, Mussauer A, Paladin A, Zink A (2022)
Presentation/Speech

Conference: 10th World Congress on Mummy Studies | Bolzano | 5.9.2022 - 9.9.2022

Mummy of vizir Imhotep: interdisciplinary study and restoration work
Facchetti F, Paladin A, Aicardi S, Manzollino R, Sutherland ML, Wurst C, Mussauer A, Samadelli M, Zink A, Greco C (2022)
Presentation/Speech

Conference: 10th World Congress on Mummy Studies | Bolzano | 5.9.2022 - 9.9.2022

Project Partners
1 - 3
  • Reiss-Engelhorn-Museen Mannheim

  • Egyptian Museum Torino

  • Egyptian Museum and Papyrus Collection Berlin

Project Team
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Projects

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Project

BOLD

Paleogenetic analysis of sixty Bolivian mummies provide precious insights into the genetic history ...

Duration: - Funding: Provincial P.-L.P. 14. Mobility ...

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