NGS ARCHAEOLOGY

The Application of next generation sequencing to Archaeology

  • Deutsch
  • English
  • Italiano
  • Project duration: September 2013 - August 2016
  • Project status:
    Finished
  • Funding:
    Internal funding EURAC (Project)
  • Total project budget: €180,000.00

The aim of this PhD project is to apply NGS (next generation sequencing) techniques to archaeological samples to retrieve biological information about individuals that would be difficult or impossible using PCR based approaches. Ancient DNA will be sequenced using techniques that continue to develop in the field of biological archaeology. Often ancient DNA is too fragmented or degraded for conventional analysis. Using NGS it is possible to sequence all the DNA present in an unbiased fashion and identify the presence of pathogen specific genotypes. The student aims to apply the latest improvements in the field of palaeogenetics to archaeological speciens. In the last decade, sequencing and computing technologies have developed to an extent that ancient DNA can be affordably and rapidly analysed. High throughput sequencing provides increased statistical weight to results allowing confident inferences to be made about the degree of contamination, degradation and even the age of the DNA. This has also expanded the range of archaeological samples that can be analysed. The researcher is involved in several projects analysing ancient DNA. The researcher is the primary researcher in three ongoing case studies: analysis of the Iceman’s clothing, metagenomic analysis of calculus from teeth and population genetics of an ancient gravesite in southern Germany.

Publications
Ancient genome-wide analyses infer kinship structure in an Early Medieval Alemannic graveyard
O'Sullivan N, Posth C, Coia V, Schuenemann VJ, Price TD, Wahl J, Pinhasi R, Zink A, Krause J, Maixner F (2018)
Journal article
Science Advances

https://doi.org/10.1126/sciadv.aao1262

http://hdl.handle.net/10863/6792

Ötzis Ledererbe - Eine Mitochondrienanalyse von Ötzis Kleidung gibt Aufschluss über die tierischen Quellen zur Lederherstellung der Kupferzeit
Maixner F, O'Sullivan N, Zink A (2016)
Journal article
Restauro

https://hdl.handle.net/10863/6669

A whole mitochondria analysis of the Tyrolean Iceman's leather provides insights into the animal sources of Copper Age clothing
O'Sullivan N, Teasdale M, Mattiangeli V, Maixner F, Pinhasi R, Bradley D, Zink A (2016)
Journal article
Scientific Reports

More information: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983343 ...

https://doi.org/10.1038/srep31279

http://hdl.handle.net/10863/6123

Partner
University College Dublin, Conway Institute
Molecular population genetics, Smurfit Institute, Trinity College
University of Tuebingen, Urgeschichte und Naturwissenschaftliche Archäologie, Abt. Paläogenetik, , Baden-Württemberg
Project Team
1 - 4

Niall James O'Sullivan

Project Manager

Projects

1 - 7
Project

MummyLabs

Development and centralization of the laboratory infrastructures of the Institute for Mummy Studies ...

Duration: December 2017 - December 2021Funding:
FESR (EU funding / Project)

view all

Institute's Projects

Institute
Eurac Research logo

Eurac Research is a private research center based in Bolzano (South Tyrol) with researchers from a wide variety of scientific fields who come from all over the globe. Together, through scientific knowledge and research, they share the goal of shaping the future.

What we do

Our research addresses the greatest challenges facing us in the future: people need health, energy, well-functioning political and social systems and an intact environment. These are complex questions, and we are seeking the answers in the interaction between many different disciplines. In so doing, our research work embraces three major themes: regions fit for living in, diversity as a life-enhancing feature, a healthy society.

Great Place To Work
ISO 9001 / 2015ISO 9001:2015
05771/0
ISO 27001ISO 27001:2013
00026/0
ORCID Member

In order to give you a better service this site uses cookies. Additionally third party cookies are used. By continuing to browse the site you are agreeing to our use of cookies.

Privacy Policy