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Data from the CHRIS population study provides the basis for understanding what makes some people resistant to hypertension therapies. The HyperProfile study research team uses biomarkers to measure th...

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Data from the CHRIS population study provides the basis for understanding what makes some people resistant to hypertension therapies. The HyperProfile study research team uses biomarkers to measure the effectiveness of certain drugs on one of the biological processes that regulate blood pressure. The next step will be to cross-reference this data with genetic data.   

The percentage of CHRIS participants with hypertension is about 24 percent. A large proportion of these participants actually brought their hypertension medications with them to their visit.  1,474 people (about 13 percent, including 60 percent men and 40 percent women) were found to have high blood pressure for the first time during the CHRIS visit and were referred to dedicated services. 
One in three people in Italy has from high blood pressure, with a slightly larger proportion of cases in men . "This data is likely to increase in the future due to the aging of the population: in fact, as the years go by, artery walls tend to become stiffer and less elastic, leading to an increase in systolic blood pressure," warns Dr. Stefano Barolo, head of the Hypertension and Cardiovascular Risk Outpatient Service at the Silandro Hospital, a partner in the study.  
If hypertension is neglected, as unfortunately often happens - especially in young people, it can lead to serious consequences. The European Society for Hypertension recalls, for example, that it increases the risk of heart attack, ischemic or hemorrhagic stroke, chronic renal failure (with dialysis as an extreme consequence), but also the risk of dementia and cognitive impairment.  

In addition to Eurac Research's Institute of Biomedicine, research partners include Silandro Hospital, the University of Glasgow and the French research institute Inserm. The study is funded with funds from Law 14 of the Autonomous Province of Bolzano. 

Institute for Biomedicine

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