We published on Scientific Reports a study showing that cigarette smoking has a consistent and generalizable association on the composition of the oral microbiota.
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The salivary microbiota of individuals who quit smoking (n = 369) showed multiple-year perturbation and tends to resemble Never smokers’ profiles within 5 years. (A) Heatmap of the relationship between the years since quitting smoking and the mean relative abundance of genera previously found significantly associated with smoking (see Fig. 1). Taxa were transformed to relative abundance and scaled by row, to highlight differences in mean abundance in relation to bins of years since quitting to limit the low sample size of some categories. Complete linkage hierarchical clustering was used to cluster columns. Since Former smokers tend to be older and given the tendency of the elderly to lose teeth, we limited the visualization to people with 20 or more teeth. (B, C, D) Relative abundance of anaerobes, aerobes and facultative anaerobes in relation to years since quitting smoking.
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